The purpose of this study was to empirically investigate the causal effect of 4-year university students’ participation in career development and employment support programs on employment outcomes(job assistance of college major knowledge, college major and job congruence, and job satisfaction). For this purpose, the hierarchical inverse probability treatment weighting(IPTW) of the propensity score was applied to increase causal inference as well as to eliminate any sample selection bias, Data from 2018 GOMS(Graduates Occupational Mobility Survey) and the Information Service of Higher Education(AcademyInfo) were used for the analysis. The results of study were as follows. First, there was a difference in the degree of university students’ participation according to the type of career development and employment support programs. Second, when controlling for student and university level covariates, the participation in career development and employment support programs was found to have a significant positive effect on the degree of job assistance of college major knowledge and job satisfaction. Third, university students’ individual characteristics (e.g., GPA, college satisfaction, life satisfaction, depression, and filed of major) as well as university characteristics (e.g., college location) were significantly related to the degree of job assistance of college major knowledge and job satisfaction. Based on these findings, we discussed the educational implications of effective interventions for encouraging university students’ participation in career development and employment support programs